Why Polynucleotides for Lips are Redefining Modern Lip Treatments

Polynucleotides for Lips: Key Benefits of NEWESTⓇ

• Dual hydration & regeneration – non-crosslinked HA deeply hydrates while polynucleotides support skin repair and quality.
• Enhances lip volume & supports skin and tissues around the mouth – naturally improves firmness, elasticity, and overall lip and peri-oral skin quality.
• Gentle, progressive results – improves skin texture, hydration, and resilience without heavy fillers.
• Treatment course & frequency – 2–3 sessions, approx 2 weeks apart; maintenance every ≅6 months for ongoing skin health if desired.
• What other areas does Newest® treat? It is versatile and can treat any areas with early signs of skin ageing
• Face (lips, peri-oral, cheeks, lower face)
• Neck, décolletage
• Upper arms, elbows & hands
• Knees.

What Are Polynucleotides and Why Are They Used for Lips?

First up, let’s talk Polynucleotides

Polynucleotides are the skincare ingredient everyone is talking about for the face and neck and are increasingly used in advanced lip treatments. Celebrated for their ability to regenerate damaged skin cells and repair collagen among many other things, they improve hydration, and soften fine lines, all without creating an unnatural or overfilled look. When applied to the lips, the results are similarly transformative. Fibroblasts are stimulated, tissue is regenerated, and the skin appears healthier, smoother, and subtly plumper.

How Do Polynucleotides for Lips Work Compared to Lip Fillers?

Traditional dermal fillers focus primarily on adding volume, which can sometimes result in lips appearing puffy or stiff. In contrast, polynucleotides for lips take a regenerative approach.

By treating both the lips and the surrounding peri-oral tissue, polynucleotides encourage natural skin renewal. This improves texture, softness, and overall lip quality while preserving natural shape and expression. The added hyaluronic acid provides gentle hydration and subtle volume that typically lasts around six months.

Polynucleotides for Lips and Fine Lines Around the Mouth

Fine lines around the upper lip, often referred to as barcode lines or smoker’s lines, can be challenging to treat. Conventional fillers may smooth these lines; however, they can sometimes compromise movement or result in an overfilled or stiff appearance

Polynucleotides for lips, delivered through NEWEST®, soften these lines gradually by improving skin quality rather than masking them with volume. The treatment supports tissue regeneration in both the lips and the surrounding peri-oral area, resulting in noticeable refinement that still looks and feels natural.

Are Polynucleotides for Lips Safe?

You may have heard polynucleotides for lips referred to as “salmon DNA injections,” but this term can be misleading. In reality, the polynucleotides used in NEWEST® are highly purified DNA fragments, carefully stripped of proteins and lipids, leaving only the regenerative components.

The science behind NEWEST® polynucleotides for lips is clean, safe, and evidence-based. Rather than simply adding filler, the treatment is designed to improve tissue health, stimulate regeneration, and support long-term skin quality.

NEWEST®: More Than a Quick Fix for Enhancement 

The beauty of NEWEST® polynucleotides for lips is that they are not a quick fix, but a strategic investment in long-term lip health. For optimal results, treatment is ideally planned a few months in advance, allowing time for subtle regeneration and for the effects to fully settle.

For those who feel hesitant about traditional lip fillers—or who want a treatment that enhances rather than alters their natural features—NEWEST® offers a refined middle ground. It delivers soft, elegant enhancement combined with genuine tissue rejuvenation.

Whether the goal is softening fine lines, gently boosting volume, or improving overall lip and peri-oral skin quality, NEWEST® polynucleotides for lips provides a modern, regenerative approach that truly goes beyond filler.