“As a clinician, I’ve seen exosome-based treatments steadily evolve over the past few years,” explains Dr. Miriam. “The latest advancement, Purasomes, is delivering consistently impressive results in both skin and hair rejuvenation. I truly believe this will become one of the most important treatments for improving skin quality in 2026 and beyond.”

But first – what exactly are Purasomes, Exosomes, and Polynucleotides?

Key Takeaways: 

• Exosomes are natural cellular messengers that communicate between cells to trigger repair, regeneration, and healing.
• Purasomes are an advanced evolution of exosome therapy, enriched with growth factors, cytokines, and vitamins for more powerful skin and hair rejuvenation.
• Polynucleotides work deeper in the skin, rebuilding structure, improving elasticity, and restoring long-term skin health.
• Purasomes (surface) and Polynucleotides (deep) work together to deliver multi-layered regeneration – refining texture, strengthening tissues, and enhancing radiance.
• Ideal for: Improving skin quality, rosacea, acne, enlarged pores, scarring, as well as scalp and hair rejuvenation, including restoring natural pigment.
• Amplified Results: When combined with treatments like microneedling, results are amplified – faster healing, firmer skin, and lasting luminosity.

Exosomes are tiny, naturally occurring cellular messengers produced by almost every cell in your body. They play a pivotal role in cell-to-cell communication, carrying vital information like proteins, lipids, and genetic material. In skincare, stem-cell-derived exosomes are used to encourage skin repair and regeneration.

Think of exosomes as couriers delivering essential information to skin cells, triggering healing processes, promoting collagen production, and reducing inflammation. They can smooth fine lines, reduce pigmentation, and restore a youthful glow.

At Dr. Miriam A, we’ve watched exosome therapy evolve:

• Plant-based exosomes: Safe and natural, but not always highly biocompatible.
• Animal-derived exosomes: Improved compatibility and regenerative potential.
• Bovine colostrum-derived Purasomes: The latest generation, showing truly exceptional results.

These intelligent messengers improve texture, tone, and elasticity, revitalizing dull, inflamed, or reactive skin, and are particularly effective for rosacea, acne, and enlarged pores.

Purasomes are an enhanced, cutting-edge form of exosome therapy. They are derived from bovine colostrum, an incredibly rich source of natural growth factors and bioactive molecules.

Created using proprietary AMPLEX Plus™ technology, Purasomes combine potent exosomes with an optimal blend of growth factors, cytokines, vitamins, and macromolecules to deliver powerful rejuvenating effects.

“Purasomes work like cellular messengers,” explains Dr. Miriam. “They carry signals that tell skin cells to repair, regenerate, and restore balance. The result is visibly healthier, smoother, and stronger skin. They are ideal for improving overall skin quality, reducing inflammation, and boosting collagen production – perfect for those with rosacea, acne, scarring, or dull complexions.”

Polynucleotides are biologically active DNA and RNA fragments that have been used for decades in regenerative medicine and have recently been adapted for aesthetic skin health.

They work by stimulating fibroblast activity – the cells responsible for producing collagen and elastin – and rebuilding the skin’s internal structure from the ground up.

“Polynucleotides are like the architects of your skin,” says Dr. Miriam. “They rebuild from within, improving firmness, hydration, and resilience.”

Unlike many surface treatments, polynucleotides restore the dermal matrix, reducing fine lines, supporting wound healing, and creating smoother, more even skin. Delivered via micro-injections or cannula, they provide deep hydration and visible rejuvenation.

When combined, Purasomes and Polynucleotides create a comprehensive, multi-layered approach to skin health, amplifying each other’s effects:

• Purasomes: Work on the surface, calming inflammation, refining texture, and brightening tone.
• Polynucleotides: Act deeply, rebuilding the skin’s scaffolding and promoting long-term structural strength.

This dual action accelerates tissue repair, stimulates collagen and elastin, supports hydration, and ensures the skin not only repairs but regenerates itself for lasting results.

These treatments are suitable for almost anyone seeking healthier, more resilient skin, but they are especially effective for:

• Rosacea and acne-prone skin: Calming inflammation and restoring balance.
• Enlarged pores and uneven texture: Refining surface smoothness.
• Pigmentation, scarring, and sun damage: Promoting deep regeneration.
• Aging skin: Rebuilding elasticity and firmness.

Hair rejuvenation: Stimulating follicles, improving density, and restoring natural pigment.

Our regenerative philosophy extends beyond facial treatments. Exosomes and Purasomes are showing exceptional promise for scalp and hair health. By stimulating dormant follicles and reactivating pigment cells, these treatments can significantly improve hair health.

The result: stronger, fuller, and more vibrant hair with each course of treatment.

Treatment frequency depends on your goals and whether we are combining therapies:

• General skin rejuvenation: 3 sessions, 2 weeks apart.
• Specific concerns (rosacea, acne, pigmentation, scarring): 4–6 sessions.
• Hair restoration: 4–6 initial sessions, with maintenance every 3–6 months.

Most clients notice a visible glow and smoother texture after just one or two sessions, with cumulative improvements over time.